Sylvie BEGIN

Sylvie BEGIN

Professeure, Chimie des Matériaux Inorganiques (DCMI)Sylvie.Begin@ipcms.unistra.fr
Tél: +33(0)3 88 10 71 92Bureau: 3003

Parcours de recherche

Head of the team “Chemical Engineering of Functional Nanomaterials (CEFUN)”.

Since september 2003: Professor at the University of Strasbourg (European Engineering School in Chemistry, Polymers and Materials) school, Research at the Institute of Physics and Chemistry of Materials (IPCMS) , UMR 7504-CNRS-UNISTRA-ECPM

September 1992 to august 2003: CNRS researcher Topic:  Physico-chemical transformations induced in oxides by high energy ball-milling

Parcours universitaire

2014 – 2021 : Director of European Engineering School in Chemistry, Polymers and Materials (ECPM).

2019-2021: President of Federation Gay Lussac

2016-2018 : Director of Collegium Science Engineering and Technology of University of Strasbourg (4 Engineering schools and 3 University Intitutes of technology)

2008-2013 : Assistant director of ECPM

2010-2014 : Director of Integrated Preparatory Cycle – Chemical International Studies (Chem. I. St.) of ECPM-FGL.

Since september 2003: Professor at the University of Strasbourg (European Engineering School in Chemistry, Polymers and Materials) school, Research at the Institute of Physics and Chemistry of Materials (IPCMS) , UMR 7504-CNRS-ULP-ECPM, Groupe Matériaux Inorganiques, 23, rue du Loess, BP43, 67034 Strasbourg Cedex 2, FRANCE.

– 09/1999: Habilitation (HDR) “Physico-chemical transformations induced in oxides by high energy ball-milling”

September 1992 to august 2003: CNRS researcher at the Laboratory of Science and Engineering of Metallurgy and Materials of the Mining School of Nancy. France

– 07/1992: PhD, Nancy I University, Nancy (Specialty: Science and Engineering of materials)

06/1989: Chemical Engineer of « Ecole Européenne des Hautes Etudes des Industries Chimiques » of Strasbourg (E.H.I.C.S) now European Engineering School in Chemistry, Polymers and Materials (ECPM).

AWARDS – 2001: Jean Rist PRICE of the French Society of Metallurgy and Materials – Since 2011 : Scientific Excellence Award – 2018 : Chevalier dans l’ordre des Palmes Académiques 

Recherches actuelles

Since 2003: Synthesis, functionalization and organization of metallic and oxide NPs for applications in energy, environment and biomedical applications: Design of oxide NPs; Organization of NPs in 2D or 3D networks; Development of theranostic nanoplateforms for biomedical; Nanocomposites based on carbonaceous materials; Magnetic nanomaterials for depollution.

1992-2003 : Physicochemical transformations induced in high energy ball-milled oxides and mechanochemistry. Synthesis of nanoparticles (NPs) of metals and oxides by an organometallic route.

Projets en cours

2020-2022: Projet Résilience Grand Est – ANR Décontamination des virus dans l’air par une approche originale combinant adsorption et photothermie.

2021-2023: MICA Conception de composites magnétiques recyclables pour la captation et le dosage de micropolluants organiques par un procédé magnéto ou photo-thermique

2021-2023: THERAGET- EuroNanoMed III – ANR Dendronized nanoparticles designed for targeted multimodal image guided therapy – 3 university partners (Belgium, Romania and France) and 2 start-ups (France and Greece)

2021-2025: ANR PHODIA Amélioration de la capture du phosphate dans le processus de dialyse péritonéale grâce à des nanostructures d’oxyde de fer recyclables spécialement conçues.

2021-2025: ANR INFINE Synthèse et contrôle des interactions dans de nouveaux nanocomposites inorganique fluoré oxyde-carbone pour la conception de matériaux d’électrodes. Coordinateur ICPEES, autres partenaires : ARMINES et ICCF- 34k€.

Publications

200 publications, 2 patents, more than 150 communications, 66 invited conference. Publications on Google Scholar: ‪‬ ‪Sylvie Begin‬ – ‪Google Scholar

Theranostic dendronized iron oxide nanoparticles
Carbon based composites for air and water depollution
[1]
F. Perton, M. Palluel, C. Kiefer, B. Freis, D. Mertz, S. Bégin-Colin, One Pot Synthesis of Dithiolane Dendron Functionalized Gold Nanoparticles, European Journal of Inorganic Chemistry. 2021 (2021) 4286–4297. https://doi.org/10.1002/ejic.202100650.
[1]
J. Bizeau, A. Adam, S. Bégin-Colin, D. Mertz, Serum Albumin Antifouling Effects of Hydroxypropyl-Cellulose and Pluronic F127 Adsorbed on Isobutyramide-Grafted Stellate Silica Nanoparticles, European Journal of Inorganic Chemistry. (2021) 4799–4805. https://doi.org/10.1002/ejic.202100678.
[1]
F. Perton, G. Cotin, C. Kiefer, J.-M. Strub, S. Cianferani, J.-M. Greneche, N. Parizel, B. Heinrich, B. Pichon, D. Mertz, S. Bégin-Colin, Iron Stearate Structures: An Original Tool for Nanoparticles Design, Inorganic Chemistry. 60 (2021) 12445–12456. https://doi.org/10.1021/acs.inorgchem.1c01689.
[1]
C. Lozano-Pedraza, E. Plaza-Mayoral, A. Espinosa, B. Sot, A. Serrano, G. Salas, C. Blanco-Andujar, G. Cotin, D. Felder-Flesch, S. Bégin-Colin, F.J. Teran, Assessing the parameters modulating optical losses of iron oxide nanoparticles under near infrared irradiation, Nanoscale Advances. (2021). https://doi.org/10.1039/d1na00601k.
[1]
G. Cotin, C. Blanco-Andujar, F. Perton, L. Asin, J.M. de la Fuente, W. Reichardt, D. Schaffner, D.-V. Ngyen, D. Mertz, C. Kiefer, F. Meyer, S. Spassov, O. Ersen, M. Chatzidakis, G.A. Botton, C. Henoumont, S. Laurent, J.-M. Greneche, F.J. Teran, D. Ortega, D. Felder-Flesch, S. Bégin-Colin, Unveiling the role of surface, size, shape and defects of iron oxide nanoparticles for theranostic applications, Nanoscale. 13 (2021) 14552–14571. https://doi.org/10.1039/d1nr03335b.
[1]
A. Adam, K. Parkhomenko, P. Duenas-Ramirez, C. Nadal, G. Cotin, P.-E. Zorn, P. Choquet, S. Bégin-Colin, D. Mertz, Orienting the Pore Morphology of Core-Shell Magnetic Mesoporous Silica with the Sol-Gel Temperature. Influence on MRI and Magnetic Hyperthermia Properties, Molecules. 26 (2021) 971. https://doi.org/10.3390/molecules26040971.
[1]
J. Kim, Y. Cho, C. Koo, C. Lee, P. Ramirez, D. Ko, J. Oh, S. Park, P. Kofinas, S. Bégin-Colin, Y. Piao, Microwave-assisted preparation of carbon coating layer on raspberry-shaped iron oxide particles for lithium-ion battery anodes, Journal of Electroanalytical Chemistry. 895 (2021) 115520. https://doi.org/10.1016/j.jelechem.2021.115520.
[1]
K. Sartori, A. Musat, F. Choueikani, J.-M. Greneche, S. Hettler, P. Bencok, S. Bégin-Colin, P. Steadman, R. Arenal, B.P. Pichon, A Detailed Investigation of the Onion Structure of Exchanged Coupled Magnetic Fe3-delta O4@CoFe2O4@Fe3-delta O4 Nanoparticles, ACS Applied Materials & Interfaces. 13 (2021) 16784–16800. https://doi.org/10.1021/acsami.0c18310.
[1]
G. Cotin, F. Perton, C. Petit, S. Sall, C. Kiefer, V. Begin, B. Pichon, C. Lefèvre, D. Mertz, J.-M. Greneche, S. Bégin-Colin, Harnessing Composition of Iron Oxide Nanoparticle: Impact of Solvent-Mediated Ligand-Ligand Interaction and Competition between Oxidation and Growth Kinetics, Chemistry of Materials. 32 (2020) 9245–9259. https://doi.org/10.1021/acs.chemmater.0c03041.
[1]
M. Dolci, J.-F. Bryche, J. Moreau, C. Leuvrey, S. Bégin-Colin, G. Barbillon, B.P. Pichon, Investigation of the structure of iron oxide nanoparticle assemblies in order to optimize the sensitivity of surface plasmon resonance-based sensors, Applied Surface Science. 527 (2020) 146773. https://doi.org/10.1016/j.apsusc.2020.146773.
[1]
P. Duenas-Ramirez, C. Bertagnolli, R. Muller, K. Sartori, A. Boos, M. Elhabiri, S. Bégin-Colin, D. Mertz, Highly chelating stellate mesoporous silica nanoparticles for specific iron removal from biological media, Journal of Colloid and Interface Science. 579 (2020) 140–151. https://doi.org/10.1016/j.jcis.2020.06.013.
[1]
D.-V. Nguyen, L. Hugoni, M. Filippi, F. Perton, D. Shi, E. Voirin, L. Power, G. Cotin, M.-P. Krafft, A. Scherberich, P. Lavalle, S. Bégin-Colin, D. Felder-Flesch, Mastering bioactive coatings of metal oxide nanoparticles and surfaces through phosphonate dendrons, New Journal of Chemistry. 44 (2020) 3206–3214. https://doi.org/10.1039/c9nj05565g.
[1]
J.R. Orives, B.P. Pichon, D. Mertz, K. Sartori, S. Bégin-Colin, W.R. Viali, S.J. Lima Ribeiro, M. Nalin, Phosphate glasses containing monodisperse Fe3-delta O4@SiO2 stellate nanoparticles obtained by melt-quenching process, Ceramics International. 46 (2020) 12120–12127. https://doi.org/10.1016/j.ceramint.2020.01.257.
[1]
K. Sartori, D. Gailly, C. Bouillet, J.-M. Greneche, P. Duenas-Ramirez, S. Bégin-Colin, F. Choueikani, B.P. Pichon, Increasing the size of Fe3-delta O4 Nanoparticles by Performing a Multistep Seed-Mediated Growth Approach, Crystal Growth & Design. 20 (2020) 1572–1582. https://doi.org/10.1021/acs.cgd.9b01300.
[1]
B. Li, S. Harlepp, V. Gensbittel, C.J.R. Wells, O. Bringel, J.G. Goetz, S. Bégin-Colin, M. Tasso, D. Begin, D. Mertz, Near infra-red light responsive carbon nanotubes@mesoporous silica for photothermia and drug delivery to cancer cells, Materials Today Chemistry. 17 (2020) 100308. https://doi.org/10.1016/j.mtchem.2020.100308.
[1]
K. Sartori, G. Cotin, C. Bouillet, V. Halté, S. Bégin-Colin, F. Choueikani, B.P. Pichon, Strong interfacial coupling through exchange interactions in soft/hard core-shell nanoparticles as a function of cationic distribution, Nanoscale. 11 (2019) 12946–12958. https://doi.org/10.1039/c9nr02323b.
[1]
F. Perton, S. Harlepp, G. Follain, K. Parkhomenko, J.G. Goetz, S. Bégin-Colin, D. Mertz, Wrapped stellate silica nanocomposites as biocompatible luminescent nanoplatforms assessed in vivo, Journal of Colloid and Interface Science. 542 (2019) 469–482. https://doi.org/10.1016/j.jcis.2019.01.098.
[1]
M. Dolci, Y. Lei, L.-M. Lacroix, C. Kiefer, C. Leuvrey, S. Bégin-Colin, B.P. Pichon, Effect of Dipolar Interactions on the Assembly Process of Iron Oxide Nanoparticles Promoted by the CuAAC “Click” Chemistry Reaction, Journal of Physical Chemistry C. 123 (2019) 27927–27936. https://doi.org/10.1021/acs.jpcc.9b08135.
[1]
G. Cotin, C. Blanco-Andujar, D.-V. Nguyen, C. Affolter, S. Boutry, A. Boos, P. Ronot, B. Uring-Lambert, P. Choquet, P.E. Zorn, D. Mertz, S. Laurent, R.N. Muller, F. Meyer, D.F. Flesch, S. Bégin-Colin, Dendron based antifouling, MRI and magnetic hyperthermia properties of different shaped iron oxide nanoparticles, Nanotechnology. 30 (2019) 374002. https://doi.org/10.1088/1361-6528/ab2998.
[1]
Z. Ferjaoui, E.J. Al Dine, A. Kulmukhamedova, L. Bezdetnaya, C.S. Chan, R. Schneider, F. Mutelet, D. Mertz, S. Bégin-Colin, F. Quiles, E. Gaffet, H. Alem, Doxorubicin-Loaded Thermoresponsive Superparamagnetic Nanocarriers for Controlled Drug Delivery and Magnetic Hyperthermia Applications, ACS Applied Materials & Interfaces. 11 (2019) 30610–30620. https://doi.org/10.1021/acsami.9b10444.
[1]
M. Menard, F. Meyer, C. Affolter-Zbaraszczuk, M. Rabineau, A. Adam, P.D. Ramirez, S. Bégin-Colin, D. Mertz, Design of hybrid protein-coated magnetic core-mesoporous silica shell nanocomposites for MRI and drug release assessed in a 3D tumor cell model, Nanotechnology. 30 (2019) 174001. https://doi.org/10.1088/1361-6528/aafe1c.
[1]
M. Rastei V., V. Pierron-Bohnes, D. Toulemon, C. Bouillet, A. Kakay, R. Hertel, E. Tetsi, S. Bégin-Colin, B.P. Pichon, Defect-Driven Magnetization Configuration of Isolated Linear Assemblies of Iron Oxide Nanoparticles, Advanced Functional Materials. 29 (2019) 1903927. https://doi.org/10.1002/adfm.201903927.
[1]
D. Shi, J. Wallyn, D.-V. Nguyen, F. Perton, D. Felder-Flesch, S. Bégin-Colin, M. Maaloum, M.P. Krafft, Microbubbles decorated with dendronized magnetic nanoparticles for biomedical imaging: effective stabilization via fluorous interactions, Beilstein Journal of Nanotechnology. 10 (2019) 2103–2115. https://doi.org/10.3762/bjnano.10.205.
[1]
K. Sartori, F. Choueikani, A. Gloter, S. Bégin-Colin, D. Taverna, B.P. Pichon, Room Temperature Blocked Magnetic Nanoparticles Based on Ferrite Promoted by a Three-Step Thermal Decomposition Process, Journal of the American Chemical Society. 141 (2019) 9783–9787. https://doi.org/10.1021/jacs.9b03965.
[1]
J. Wallyn, N. Anton, D. Mertz, S. Bégin-Colin, F. Perton, C.A. Serra, F. Franconi, L. Lemaire, M. Chiper, H. Libouban, N. Messaddeq, H. Anton, T.F. Vandamme, Magnetite- and Iodine-Containing Nanoemulsion as a Dual Modal Contrast Agent for X-ray/Magnetic Resonance Imaging, ACS Applied Materials & Interfaces. 11 (2019) 403–416. https://doi.org/10.1021/acsami.8b19517.
[1]
F. Perton, M. Tasso, G.A. Munoz Medina, M. Menard, C. Blanco-Andujar, E. Portiansky, M.B. Fernandez van Raap, D. Begin, F. Meyer, S. Bégin-Colin, D. Mertz, Fluorescent and magnetic stellate mesoporous silica for bimodal imaging and magnetic hyperthermia, Applied Materials Today. 16 (2019) 301–314. https://doi.org/10.1016/j.apmt.2019.06.006.
[1]
M. Ménard, F. Meyer, K. Parkhomenko, C. Leuvrey, G. Francius, S. Bégin-Colin, D. Mertz, Mesoporous silica templated-albumin nanoparticles with high doxorubicin payload for drug delivery assessed with a 3-D tumor cell model, Biochimica et Biophysica Acta (BBA) - General Subjects. 1863 (2019) 332–341. https://doi.org/10.1016/j.bbagen.2018.10.020.
[1]
M. Dolci, Y. Liu, X. Liu, C. Leuvrey, A. Derory, D. Begin, S. Bégin-Colin, B.P. Pichon, Exploring Exchange Bias Coupling in Fe3-O4@CoO Core-Shell Nanoparticle 2D Assemblies, Advanced Functional Materials. 28 (2018) 1706957. https://doi.org/10.1002/adfm.201706957.
[1]
G. Cotin, C. Kiefer, F. Perton, D. Ihiawakrim, C. Blanco-Andujar, S. Moldovan, C. Lefèvre, O. Ersen, B. Pichon, D. Mertz, S. Bégin-Colin, Unravelling the Thermal Decomposition Parameters for The Synthesis of Anisotropic Iron Oxide Nanoparticles, Nanomaterials. 8 (2018) 881. https://doi.org/10.3390/nano8110881.
[1]
C. Bordeianu, A. Parat, S. Piant, A. Walter, C. Zbaraszczuk-Affolter, F. Meyer, S. Bégin-Colin, S. Boutry, R.N. Muller, E. Jouberton, J.-M. Chezal, B. Labeille, E. Cinotti, J.-L. Perrot, E. Miot-Noirault, S. Laurent, D. Felder-Flesch, Evaluation of the Active Targeting of Melanin Granules after Intravenous Injection of Dendronized Nanoparticles, Molecular Pharmaceutics. 15 (2018) 536–547. https://doi.org/10.1021/acs.molpharmaceut.7b00904.
[1]
W. Baaziz, B.P. Pichon, J.-M. Greneche, S. Bégin-Colin, Effect of reaction environment and in situ formation of the precursor on the composition and shape of iron oxide nanoparticles synthesized by the thermal decomposition method, CrystEngComm. 20 (2018) 7206–7220. https://doi.org/10.1039/c8ce00875b.
[1]
Y. Liu, X. Liu, M. Dolci, C. Leuvrey, E. Pardieu, A. Derory, D. Bégin, S. Bégin-Colin, B.P. Pichon, Investigation of the Collective Properties in Monolayers of Exchange-Biased Fe3-delta O-4@CoO Core-Shell Nanoparticles, Journal of Physical Chemistry C. 122 (2018) 17456–17464. https://doi.org/10.1021/acs.jpcc.8b04615.
[1]
G.E. Fenoy, B. Van der Schueren, J. Scotto, F. Boulmedais, M.R. Ceolin, S. Bégin-Colin, D. Bégin, W.A. Marmisolle, O. Azzaroni, Layer-by-layer assembly of iron oxide-decorated few-layer graphene/PANI:PSS composite films for high performance supercapacitors operating in neutral aqueous electrolytes, Electrochimica Acta. 283 (2018) 1178–1187. https://doi.org/10.1016/j.electacta.2018.07.085.
[1]
D. Elgrabli, W. Dachraoui, H. de Marmier, C. Menard-Moyon, D. Begin, S. Bégin-Colin, A. Bianco, D. Alloyeau, F. Gazeau, Intracellular degradation of functionalized carbon nanotube/iron oxide hybrids is modulated by iron via Nrf2 pathway, Scientific Reports. 7 (2017) 40997. https://doi.org/10.1038/srep40997.
[1]
G. Melinte, S. Moldovan, C. Hirlimann, W. Baaziz, S. Bégin-Colin, C. Pham-Huu, O. Ersen, Catalytic Nanopatterning of Few-Layer Graphene, ACS Catalysis. 7 (2017) 5941–5949. https://doi.org/10.1021/acscatal.7b01777.
[1]
D. Mertz, O. Sandre, S. Bégin-Colin, Drug releasing nanoplatforms activated by alternating magnetic fields, Biochimica et Biophysica Acta-General Subjects. 1861 (2017) 1617–1641. https://doi.org/10.1016/j.bbagen.2017.02.025.
[1]
A. Walter, A. Garofalo, P. Bonazza, F. Meyer, H. Martinez, S. Fleutot, C. Billotey, J. Taleb, D. Felder-Flesch, S. Bégin-Colin, Effect of the Functionalization Process on the Colloidal, Magnetic Resonance Imaging, and Bioelimination Properties of Mono- or Bisphosphonate-Anchored Dendronized Iron Oxide Nanoparticles, ChemPlusChem. 82 (2017) 647–659. https://doi.org/10.1002/cplu.201700049.
[1]
C. Blanco-Andujar, A. Walter, G. Cotin, C. Bordeianu, D. Mertz, D. Felder-Flesch, S. Bégin-Colin, Design of iron oxide-based nanoparticles for MRI and magnetic hyperthermia, Nanomedicine. 11 (2016) 1889–1910. https://doi.org/10.2217/nnm-2016-5001.
[1]
S.A. Chechetka, M. Doi, B.P. Pichon, S. Bégin-Colin, E. Miyako, Photothermal and mechanical stimulation of cells via dualfunctional nanohybrids, Nanotechnology. 27 (2016) 475102. https://doi.org/10.1088/0957-4484/27/47/475102.
[1]
R. Hachani, M. Lowdell, M. Birchall, A. Hervault, D. Mertz, S. Bégin-Colin, N.T.K. Thanh, Polyol synthesis, functionalisation, and biocompatibility studies of superparamagnetic iron oxide nanoparticles as potential MRI contrast agents, Nanoscale. 8 (2016) 3278–3287. https://doi.org/10.1039/c5nr03867g.
[1]
G. Klughertz, G. Manfredi, P.-A. Hervieux, B.P. Pichon, S. Bégin-Colin, Effect of Disorder and Dipolar Interactions in Two-Dimensional Assemblies of Iron-Oxide Magnetic Nanoparticles, Journal of Physical Chemistry C. 120 (2016) 7381–7387. https://doi.org/10.1021/acs.jpcc.6b00254.
[1]
D. Toulemon, M.V. Rastei, D. Schmool, J. Saiz Garitaonandia, L. Lezama, X. Cattoen, S. Bégin-Colin, B.P. Pichon, Enhanced Collective Magnetic Properties Induced by the Controlled Assembly of Iron Oxide Nanoparticles in Chains, Advanced Functional Materials. 26 (2016) 2454–2462. https://doi.org/10.1002/adfm.201505086.
[1]
M. Vural, O. Gerber, B.P. Pichon, S. Lemonnier, E. Barraud, L.C. Kempel, S. Bégin-Colin, P. Kofinas, Stretchable magneto-dielectric composites based on raspberry-shaped iron oxide nanostructures, Journal of Materials Chemistry C. 4 (2016) 2345–2352. https://doi.org/10.1039/c6tc00419a.
[1]
X.-Y. Wang, D. Mertz, C. Blanco-Andujar, A. Bora, M. Menard, F. Meyer, C. Giraudeau, S. Bégin-Colin, Optimizing the silanization of thermally-decomposed iron oxide nanoparticles for efficient aqueous phase transfer and MRI applications, RSC Advances. 6 (2016) 93784–93793. https://doi.org/10.1039/c6ra18360c.
[1]
O. Gerber, S. Bégin-Colin, B.P. Pichon, E. Barraud, S. Lemonnier, C. Pham-Huu, B. Daffos, P. Simon, J. Come, D. Begin, Design of Fe3-xO4 raspberry decorated graphene nanocomposites with high performances in lithium-ion battery, Journal of Energy Chemistry. 25 (2016) 272–277. https://doi.org/10.1016/j.jechem.2016.01.021.