Chemical Engineering of Functional Nanomaterials

Purpose

The CEFUN team aims at designing original nanostructures…

Main research interests deal with

News

Welcome our new team member…

Ongoing Project

Project name, funder, scientific head, aim

Team members

Permanent staf

Sylvie Bégin-Colin

Anne Carton

Damien Mertz

Benoit Pichon

Post-doc, PhD student, Master student

Publications

[1]
C. Wells, O. Vollin-Bringel, V. Fiegel, S. Harlepp, B. Van der Schueren, S. Bégin-Colin, D. Bégin, D. Mertz, Engineering of Mesoporous Silica Coated Carbon-Based Materials Optimized for an Ultrahigh Doxorubicin Payload and a Drug Release Activated by pH, T, and NIR-light, Advanced Functional Materials. 28 (2018). https://doi.org/10.1002/adfm.201706996.
[1]
X.-Y. Wang, D. Mertz, C. Blanco-Andujar, A. Bora, M. Menard, F. Meyer, C. Giraudeau, S. Bégin-Colin, Optimizing the silanization of thermally-decomposed iron oxide nanoparticles for efficient aqueous phase transfer and MRI applications, RSC Advances. 6 (2016) 93784–93793. https://doi.org/10.1039/c6ra18360c.
[1]
A. Walter, A. Garofalo, P. Bonazza, F. Meyer, H. Martinez, S. Fleutot, C. Billotey, J. Taleb, D. Felder-Flesch, S. Bégin-Colin, Effect of the Functionalization Process on the Colloidal, Magnetic Resonance Imaging, and Bioelimination Properties of Mono- or Bisphosphonate-Anchored Dendronized Iron Oxide Nanoparticles, ChemPlusChem. 82 (2017) 647–659. https://doi.org/10.1002/cplu.201700049.
[1]
A. Walter, A. Garofalo, A. Parat, H. Martinez, D. Felder-Flesch, S. Bégin-Colin, Functionalization strategies and dendronization of iron oxide nanoparticles, Nanotechnology Reviews. 4 (2015) 581–593. https://doi.org/10.1515/ntrev-2015-0014.
[1]
A. Walter, A. Parat, A. Garofalo, S. Laurent, L.V. Elst, R.N. Muller, T. Wu, E. Heuillard, E. Robinet, F. Meyer, D. Felder-Flesch, S. Bégin-Colin, Modulation of Relaxivity, Suspension Stability, and Biodistribution of Dendronized Iron Oxide Nanoparticles as a Function of the Organic Shell Design, Particle & Particle Systems Characterization. 32 (2015) 552–560. https://doi.org/10.1002/ppsc.201400217.
[1]
A. Walter, C. Billotey, A. Garofalo, C. Ulhaq-Bouillet, C. Lefèvre, J. Taleb, S. Laurent, L. Vander Elst, R.N. Muller, L. Lartigue, F. Gazeau, D. Felder-Flesch, S. Bégin-Colin, Mastering the Shape and Composition of Dendronized Iron Oxide Nanoparticles To Tailor Magnetic Resonance Imaging and Hyperthermia, Chemistry of Materials. 26 (2014) 5252–5264. https://doi.org/10.1021/cm5019025.
[1]
A. Walter, A. Garofalo, A. Parat, J. Jouhannaud, G. Pourroy, E. Voirin, S. Laurent, P. Bonazza, J. Taleb, C. Billotey, L.V. Elst, R.N. Muller, S. Bégin-Colin, D. Felder-Flesch, Validation of a dendron concept to tune colloidal stability, MRI relaxivity and bioelimination of functional nanoparticles, Journal of Materials Chemistry B. 3 (2015) 1484–1494. https://doi.org/10.1039/c4tb01954g.
[1]
J. Wallyn, N. Anton, D. Mertz, S. Bégin-Colin, F. Perton, C.A. Serra, F. Franconi, L. Lemaire, M. Chiper, H. Libouban, N. Messaddeq, H. Anton, T.F. Vandamme, Magnetite- and Iodine-Containing Nanoemulsion as a Dual Modal Contrast Agent for X-ray/Magnetic Resonance Imaging, ACS Applied Materials & Interfaces. 11 (2019) 403–416. https://doi.org/10.1021/acsami.8b19517.
[1]
M. Vural, O. Gerber, B.P. Pichon, S. Lemonnier, E. Barraud, L.C. Kempel, S. Bégin-Colin, P. Kofinas, Stretchable magneto-dielectric composites based on raspberry-shaped iron oxide nanostructures, Journal of Materials Chemistry C. 4 (2016) 2345–2352. https://doi.org/10.1039/c6tc00419a.
[1]
L. Truong-Phuoc, M. Kueny-Stotz, J. Jouhannaud, A. Garofalo, F.-X. Ble, H. Simon, F. Tellier, P. Poulet, P. Chirco, S. Bégin-Colin, G. Pourroy, D. Felder-Flesch, Patent Blue Derivatized Dendronized Iron Oxide Nanoparticles for Multimodal Imaging, European Journal of Inorganic Chemistry. (2015) 4565–4571. https://doi.org/10.1002/ejic.201500289.
[1]
D. Toulemon, M.V. Rastei, D. Schmool, J. Saiz Garitaonandia, L. Lezama, X. Cattoen, S. Bégin-Colin, B.P. Pichon, Enhanced Collective Magnetic Properties Induced by the Controlled Assembly of Iron Oxide Nanoparticles in Chains, Advanced Functional Materials. 26 (2016) 2454–2462. https://doi.org/10.1002/adfm.201505086.
[1]
D. Toulemon, B.P. Pichon, X. Cattoen, M.W.C. Man, S. Bégin-Colin, 2D assembly of non-interacting magnetic iron oxide nanoparticles via “click” chemistry, Chemical Communications. 47 (2011) 11954–11956. https://doi.org/10.1039/c1cc14661k.
[1]
D. Toulemon, Y. Liu, X. Cattoen, C. Leuvrey, S. Bégin-Colin, B.P. Pichon, Enhanced Collective Magnetic Properties in 2D Monolayers of Iron Oxide Nanoparticles Favored by Local Order and Local 1D Shape Anisotropy, Langmuir. 32 (2016) 1621–1628. https://doi.org/10.1021/acs.langmuir.5b04145.
[1]
D. Toulemon, B.P. Pichon, C. Leuvrey, S. Zafeiratos, V. Papaefthimiou, X. Cattoën, S. Bégin-Colin, Fast Assembling of Magnetic Iron Oxide Nanoparticles by Microwave-Assisted Copper(I) Catalyzed Alkyne–Azide Cycloaddition (CuAAC), Chemistry of Materials. 25 (2013) 2849–2854. https://doi.org/10.1021/cm401326p.
[1]
E. Terrier, Y. Liu, B.P. Pichon, S. Bégin-Colin, V. Halté, Ultrafast demagnetization in Fe 3 O 4 and γ ‒Fe 2 O 3 nanoparticles: the role of enhanced antiferromagnetic exchange interaction, Journal of Physics D: Applied Physics. 49 (2016) 505001. https://doi.org/10.1088/0022-3727/49/50/505001.
[1]
D. Shi, J. Wallyn, D.-V. Nguyen, F. Perton, D. Felder-Flesch, S. Bégin-Colin, M. Maaloum, M.P. Krafft, Microbubbles decorated with dendronized magnetic nanoparticles for biomedical imaging: effective stabilization via fluorous interactions, Beilstein Journal of Nanotechnology. 10 (2019) 2103–2115. https://doi.org/10.3762/bjnano.10.205.
[1]
V. Sepelak, S. Bégin-Colin, G. Le Caer, Transformations in oxides induced by high-energy ball-milling, Dalton Transactions. 41 (2012) 11927–48. https://doi.org/10.1039/c2dt30349c.
[1]
L. Schlur, S. Bégin-Colin, P. Gilliot, M. Gallart, G. Carre, S. Zafeiratos, N. Keller, V. Keller, P. Andre, J.-M. Greneche, B. Hezard, M.-H. Desmonts, G. Pourroy, Effect of ball-milling and Fe-/Al-doping on the structural aspect and visible light photocatalytic activity of TiO2 towards Escherichia coli bacteria abatement, Materials Science & Engineering C-Materials for Biological Applications. 38 (2014) 11–19. https://doi.org/10.1016/j.msec.2014.01.026.
[1]
K. Sartori, G. Cotin, C. Bouillet, V. Halté, S. Bégin-Colin, F. Choueikani, B.P. Pichon, Strong interfacial coupling through exchange interactions in soft/hard core-shell nanoparticles as a function of cationic distribution, Nanoscale. 11 (2019) 12946–12958. https://doi.org/10.1039/c9nr02323b.
[1]
K. Sartori, D. Gailly, C. Bouillet, J.-M. Greneche, P. Duenas-Ramirez, S. Bégin-Colin, F. Choueikani, B.P. Pichon, Increasing the size of Fe3-delta O4 Nanoparticles by Performing a Multistep Seed-Mediated Growth Approach, Crystal Growth & Design. 20 (2020) 1572–1582. https://doi.org/10.1021/acs.cgd.9b01300.
[1]
K. Sartori, F. Choueikani, A. Gloter, S. Bégin-Colin, D. Taverna, B.P. Pichon, Room Temperature Blocked Magnetic Nanoparticles Based on Ferrite Promoted by a Three-Step Thermal Decomposition Process, Journal of the American Chemical Society. 141 (2019) 9783–9787. https://doi.org/10.1021/jacs.9b03965.
[1]
K. Sartori, A. Musat, F. Choueikani, J.-M. Greneche, S. Hettler, P. Bencok, S. Bégin-Colin, P. Steadman, R. Arenal, B.P. Pichon, A Detailed Investigation of the Onion Structure of Exchanged Coupled Magnetic Fe3-delta O4@CoFe2O4@Fe3-delta O4 Nanoparticles, ACS Applied Materials & Interfaces. 13 (2021) 16784–16800. https://doi.org/10.1021/acsami.0c18310.
[1]
J.S. Salazar, L. Perez, O. de Abril, L.T. Phuoc, D. Ihiawakrim, M. Vazquez, J.-M. Greneche, S. Bégin-Colin, G. Pourroy, Magnetic Iron Oxide Nanoparticles in 10-40 nm Range: Composition in Terms of Magnetite/Maghemite Ratio and Effect on the Magnetic Properties, Chemistry of Materials. 23 (2011) 1379–1386. https://doi.org/10.1021/cm103188a.
[1]
G. Rydzek, D. Toulemon, A. Garofalo, C. Leuvrey, J.-F. Dayen, D. Felder-Flesch, P. Schaaf, L. Jierry, S. Bégin-Colin, B.P. Pichon, F. Boulmedais, Selective Nanotrench Filling by One-Pot Electroclick Self-Constructed Nanoparticle Films, Small. 11 (2015) 4638–4642. https://doi.org/10.1002/smll.201500639.
[1]
M. Rastei V., V. Pierron-Bohnes, D. Toulemon, C. Bouillet, A. Kakay, R. Hertel, E. Tetsi, S. Bégin-Colin, B.P. Pichon, Defect-Driven Magnetization Configuration of Isolated Linear Assemblies of Iron Oxide Nanoparticles, Advanced Functional Materials. 29 (2019) 1903927. https://doi.org/10.1002/adfm.201903927.
[1]
J. Pivetal, M. Frenea-Robin, N. Haddour, C. Vezy, L.F. Zanini, G. Ciuta, N.M. Dempsey, F. Dumas-Bouchiat, G. Reyne, S. Bégin-Colin, D. Felder-Flesh, C. Ghobril, G. Pourroy, P. Simonet, Development and applications of a DNA labeling method with magnetic nanoparticles to study the role of horizontal gene transfer events between bacteria in soil pollutant bioremediation processes, Environmental Science and Pollution Research. 22 (2015) 20322–20327. https://doi.org/10.1007/s11356-015-5614-0.
[1]
B.P. Pichon, O. Gerber, C. Lefèvre, I. Florea, S. Fleutot, W. Baaziz, M. Pauly, M. Ohlmann, C. Ulhaq, O. Ersen, V. Pierron-Bohnes, P. Panissod, M. Drillon, S. Bégin-Colin, Microstructural and Magnetic Investigations of Wüstite-Spinel Core-Shell Cubic-Shaped Nanoparticles, Chemistry of Materials. 23 (2011) 2886–2900. https://doi.org/10.1021/cm2003319.
[1]
B.P. Pichon, P. Louet, O. Felix, M. Drillon, S. Bégin-Colin, G. Decher, Magnetotunable Hybrid Films of Stratified Iron Oxide Nanoparticles Assembled by the Layer-by-Layer Technique, Chemistry of Materials. 23 (2011) 3668–3675. https://doi.org/10.1021/cm201139s.
[1]
B.P. Pichon, M. Pauly, P. Marie, C. Leuvrey, S. Bégin-Colin, Tunable Magnetic Properties of Nanoparticle Two-Dimensional Assemblies Addressed by Mixed Self-Assembled Monolayers, Langmuir. 27 (2011) 6235–6243. https://doi.org/10.1021/la105052z.
[1]
B.P. Pichon, G. Barbillon, P. Marie, M. Pauly, S. Bégin-Colin, Iron oxide magnetic nanoparticles used as probing agents to study the nanostructure of mixed self-assembled monolayers, Nanoscale. 3 (2011) 4696–4705. https://doi.org/10.1039/c1nr10729a.
[1]
B.P. Pichon, C. Leuvey, D. Ihawakrim, P. Bernard, G. Schmerber, S. Bégin-Colin, Magnetic Properties of Mono- and Multilayer Assemblies of Iron Oxide Nanoparticles Promoted by SAMs, Journal of Physical Chemistry C. 118 (2014) 3828–3837. https://doi.org/10.1021/jp412174k.
[1]
B.P. Pichon, P. Buchwalter, C. Carcel, X. Cattoën, M. Wong Chi Man, S. Bégin-Colin, Assembling of Magnetic Iron Oxide Nanoparticles Controlled by Self-assembled Monolayers of Trialkoxysilane Molecules, The Open Surface Science Journal. 4 (2012) 35–41. https://doi.org/10.2174/1876531901204010035.
[1]
F. Perton, M. Palluel, C. Kiefer, B. Freis, D. Mertz, S. Bégin-Colin, One Pot Synthesis of Dithiolane Dendron Functionalized Gold Nanoparticles, European Journal of Inorganic Chemistry. 2021 (2021) 4286–4297. https://doi.org/10.1002/ejic.202100650.
[1]
F. Perton, G. Cotin, C. Kiefer, J.-M. Strub, S. Cianferani, J.-M. Greneche, N. Parizel, B. Heinrich, B. Pichon, D. Mertz, S. Bégin-Colin, Iron Stearate Structures: An Original Tool for Nanoparticles Design, Inorganic Chemistry. 60 (2021) 12445–12456. https://doi.org/10.1021/acs.inorgchem.1c01689.
[1]
F. Perton, S. Harlepp, G. Follain, K. Parkhomenko, J.G. Goetz, S. Bégin-Colin, D. Mertz, Wrapped stellate silica nanocomposites as biocompatible luminescent nanoplatforms assessed in vivo, Journal of Colloid and Interface Science. 542 (2019) 469–482. https://doi.org/10.1016/j.jcis.2019.01.098.
[1]
F. Perton, M. Tasso, G.A. Munoz Medina, M. Menard, C. Blanco-Andujar, E. Portiansky, M.B. Fernandez van Raap, D. Begin, F. Meyer, S. Bégin-Colin, D. Mertz, Fluorescent and magnetic stellate mesoporous silica for bimodal imaging and magnetic hyperthermia, Applied Materials Today. 16 (2019) 301–314. https://doi.org/10.1016/j.apmt.2019.06.006.
[1]
M. Pauly, B.P. Pichon, P.-A. Albouy, S. Fleutot, C. Leuvrey, M. Trassin, J.-L. Gallani, S. Bégin-Colin, Monolayer and multilayer assemblies of spherically and cubic-shaped iron oxide nanoparticles, Journal of Materials Chemistry. 21 (2011) 16018–16027. https://doi.org/10.1039/c1jm12012c.
[1]
M. Pauly, J.-F. Dayen, D. Golubev, J.-B. Beaufrand, B.P. Pichon, B. Doudin, S. Bégin-Colin, Co-tunneling Enhancement of the Electrical Response of Nanoparticle Networks, Small. 8 (2012) 108–115. https://doi.org/10.1002/smll.201100931.
[1]
M. Pauly, B.P. Pichon, P. Panissod, S. Fleutot, P. Rodriguez, M. Drillon, S. Bégin-Colin, Size dependent dipolar interactions in iron oxide nanoparticle monolayer and multilayer Langmuir-Blodgett films, Journal of Materials Chemistry. 22 (2012) 6343–6350. https://doi.org/10.1039/c2jm15797g.
[1]
E. Pardieu, S. Pronkin, M. Dolci, T. Dintzer, B.P. Pichon, D. Begin, C. Pham-Huu, P. Schaaf, S. Bégin-Colin, F. Boulmedais, Hybrid layer-by-layer composites based on a conducting polyelectrolyte and Fe3O4 nanostructures grafted onto graphene for supercapacitor application, Journal of Materials Chemistry A. 3 (2015) 22877–22885. https://doi.org/10.1039/c5ta05132k.
[1]
A. Parat, C. Bordeianu, H. Dib, A. Garofalo, A. Walter, S. Bégin-Colin, D. Felder-Flesch, Dendrimer-nanoparticle conjugates in nanomedicine, Nanomedicine. 10 (2015) 977–992. https://doi.org/10.2217/NNM.14.196.
[1]
J.R. Orives, B.P. Pichon, D. Mertz, K. Sartori, S. Bégin-Colin, W.R. Viali, S.J. Lima Ribeiro, M. Nalin, Phosphate glasses containing monodisperse Fe3-delta O4@SiO2 stellate nanoparticles obtained by melt-quenching process, Ceramics International. 46 (2020) 12120–12127. https://doi.org/10.1016/j.ceramint.2020.01.257.
[1]
D.-V. Nguyen, L. Hugoni, M. Filippi, F. Perton, D. Shi, E. Voirin, L. Power, G. Cotin, M.-P. Krafft, A. Scherberich, P. Lavalle, S. Bégin-Colin, D. Felder-Flesch, Mastering bioactive coatings of metal oxide nanoparticles and surfaces through phosphonate dendrons, New Journal of Chemistry. 44 (2020) 3206–3214. https://doi.org/10.1039/c9nj05565g.
[1]
E. Miyako, B.P. Pichon, C. Menard-Moyon, I.A. Vacchi, C. Lefèvre, S. Bégin-Colin, A. Bianco, Design, synthesis, characterization and properties of magnetic nanoparticle-nanocarbon hybrids, Carbon. 96 (2016) 49–56. https://doi.org/10.1016/j.carbon.2015.09.045.
[1]
D. Mertz, O. Sandre, S. Bégin-Colin, Drug releasing nanoplatforms activated by alternating magnetic fields, Biochimica et Biophysica Acta-General Subjects. 1861 (2017) 1617–1641. https://doi.org/10.1016/j.bbagen.2017.02.025.
[1]
M. Menard, F. Meyer, C. Affolter-Zbaraszczuk, M. Rabineau, A. Adam, P.D. Ramirez, S. Bégin-Colin, D. Mertz, Design of hybrid protein-coated magnetic core-mesoporous silica shell nanocomposites for MRI and drug release assessed in a 3D tumor cell model, Nanotechnology. 30 (2019) 174001. https://doi.org/10.1088/1361-6528/aafe1c.
[1]
M. Ménard, F. Meyer, K. Parkhomenko, C. Leuvrey, G. Francius, S. Bégin-Colin, D. Mertz, Mesoporous silica templated-albumin nanoparticles with high doxorubicin payload for drug delivery assessed with a 3-D tumor cell model, Biochimica et Biophysica Acta (BBA) - General Subjects. 1863 (2019) 332–341. https://doi.org/10.1016/j.bbagen.2018.10.020.
[1]
G. Melinte, S. Moldovan, C. Hirlimann, W. Baaziz, S. Bégin-Colin, C. Pham-Huu, O. Ersen, Catalytic Nanopatterning of Few-Layer Graphene, ACS Catalysis. 7 (2017) 5941–5949. https://doi.org/10.1021/acscatal.7b01777.
[1]
G. Melinte, I. Florea, S. Moldovan, I. Janowska, W. Baaziz, R. Arenal, A. Wisnet, C. Scheu, S. Bégin-Colin, D. Begin, C. Pham-Huu, O. Ersen, A 3D insight on the catalytic nanostructuration of few-layer graphene, Nature Communications. 5 (2014) 4109. https://doi.org/10.1038/ncomms5109.
[1]
G. Melinte, S. Moldovan, C. Hirlimann, X. Liu, S. Bégin-Colin, D. Begin, F. Banhart, C. Pham-Huu, O. Ersen, Towards nanoprinting with metals on graphene, Nature Communications. 6 (2015) 8071. https://doi.org/10.1038/ncomms9071.