10 February 2022

Seminar DMCI presented by Francisco J. Terán

"Probing interactions between magnetic nanoparticles and biological entities by AC magnetometry"

iMdea Nanociencia, Campus Universitario de Cantoblanco, 28049 Madrid, Spain
Nanobiotecnología (iMdea Nanociencia), Unidad Asociada al Centro Nacional de Biotecnología-CSIC , Campus Universitario de Cantoblanco, 28049 Madrid, Spain
Nanotech Solutions SL, Ctra Madrid 23, 40150 Villacastín, Spain

By Zoom :

https://us02web.zoom.us/j/83516680265?pwd=ZXMrZjNNR2xlSFlNTFdQZTJmMUU2Zz09
Meeting ID : 835 1668 0265
Secret code : v1fGRa

Abstract : Nowadays, the progress of nanoparticle engineering enables the synthesis of magnetic nanocrystals with customized physical, chemical, and/or biological properties. Recent works underline the influence of biological entities on determining the magnetic response of magnetic nanoparticles under alternating magnetic fields. Here, I will present some examples showing the potential of AC magnetometry for probing the interactions between magnetic nanoparticles and biological molecules and cells. First, the elucidation of the colloidal stability of iron oxide nanoparticles under physiological conditions1,3. Second, the influence of cell internalization on the dynamical magnetic response of iron oxide nanoparticles.2 Finally, the potential of using AC magnetometry as a powerful and useful tool for quick characterization of the distinct bioconjugation steps of magnetic nanoparticles with recognition ligands and drugs will be shown.

  • 1.- A. Aires et al. Chem.Nano.Mat 2016 DOI: 10.1002/cnma.201600333
  • 2.- D. Cabrera et al. ACS Nano 12(3), 2741 (2018)
  • 3.- A. Aires et al. METHOD FOR DETECTION OF AN ANALYTE; Patent application: WO2019/092131
10 February 2022, 11h0012h00
En visioconférence

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