Damien MERTZ

Damien MERTZ

Researcher, Inorganic Materials Chemistry (DCMI)Damien.Mertz@ipcms.unistra.fr
Phone: +33(0)3 88 10 71 90Office: 3004

Research background

2018 : Habilitation for research direction (HDR), University of Strasbourg, France

Since 2013: CNRS researcher (Chargé de recherche) at IPCMS, University of Strasbourg, France

2011 – 2013: Postdoctoral fellowship, INSERM and IHU Strasbourg       

2009 – 2011 : Postdoctoral fellowship, University of Melbourne, Australia,

Academic background

2008 : PhD in Physical Chemistry, University of Strasbourg

2005 : M.Sc. in Polymers, Materials and Surfaces, University of Strasbourg

Current research

I develop my research activity at IPCMS, Strasbourg, CNRS UMR 7504, working on the synthesis and functionalization of nanoparticles for health applications. My research topics include:

  • Protein–based nanocarriers via mesoporous silica templating for drug delivery applications
  • Functional mesoporous nanosilica for bioimaging and biodepollution applications.
  • Magnetic core-shells for MRI, magnetic hyperthermia and drug delivery
  • NIR-light responsive mesoporous silica coated carbon-based materials for phototherapy and drug delivery

Publications

[1]
B. Li, M. Criado-Gonzalez, A. Adam, J. Bizeau, C. Melart, A. Carvalho, S. Bégin, D. Begin, L. Jierry, D. Mertz, Peptide Hydrogels Assembled from Enzyme-Adsorbed Mesoporous Silica Nanostructures for Thermoresponsive Doxorubicin Release, ACS Applied Nano Materials. 5 (2022) 120–125. https://doi.org/10.1021/acsanm.1c03959.
[1]
F. Perton, M. Palluel, C. Kiefer, B. Freis, D. Mertz, S. Bégin-Colin, One Pot Synthesis of Dithiolane Dendron Functionalized Gold Nanoparticles, European Journal of Inorganic Chemistry. 2021 (2021) 4286–4297. https://doi.org/10.1002/ejic.202100650.
[1]
F. Perton, G. Cotin, C. Kiefer, J.-M. Strub, S. Cianferani, J.-M. Greneche, N. Parizel, B. Heinrich, B. Pichon, D. Mertz, S. Bégin-Colin, Iron Stearate Structures: An Original Tool for Nanoparticles Design, Inorganic Chemistry. 60 (2021) 12445–12456. https://doi.org/10.1021/acs.inorgchem.1c01689.
[1]
A. Mohanty, C.D. Viet, A.-C. Roger, A. Adam, D. Mertz, W. Baaziz, I. Janowska, Structural impact of carbon nanofibers/few-layer-graphene substrate decorated with Ni for CO2 methanation via inductive heating, Applied Catalysis B-Environmental. 298 (2021). https://doi.org/10.1016/j.apcatb.2021.120589.
[1]
K. Katcko, E. Urbain, F. Ngassam, L. Kandpal, B. Chowrira, F. Schleicher, U. Halisdemir, D. Wang, T. Scherer, D. Mertz, B. Leconte, N. Beyer, D. Spor, P. Panissod, A. Boulard, J. Arabski, C. Kieber, E. Sternitzky, V. Costa, M. Hehn, F. Montaigne, A. Bahouka, W. Weber, E. Beaurepaire, C. Kubel, D. Lacour, M. Alouani, S. Boukari, M. Bowen, Encoding Information on the Excited State of a Molecular Spin Chain, Advanced Functional Materials. 31 (2021) 2009467. https://doi.org/10.1002/adfm.202009467.
[1]
G. Cotin, C. Blanco-Andujar, F. Perton, L. Asin, J.M. de la Fuente, W. Reichardt, D. Schaffner, D.-V. Ngyen, D. Mertz, C. Kiefer, F. Meyer, S. Spassov, O. Ersen, M. Chatzidakis, G.A. Botton, C. Henoumont, S. Laurent, J.-M. Greneche, F.J. Teran, D. Ortega, D. Felder-Flesch, S. Bégin-Colin, Unveiling the role of surface, size, shape and defects of iron oxide nanoparticles for theranostic applications, Nanoscale. 13 (2021) 14552–14571. https://doi.org/10.1039/d1nr03335b.
[1]
J. Bizeau, A. Adam, S. Bégin-Colin, D. Mertz, Serum Albumin Antifouling Effects of Hydroxypropyl-Cellulose and Pluronic F127 Adsorbed on Isobutyramide-Grafted Stellate Silica Nanoparticles, European Journal of Inorganic Chemistry. (2021) 4799–4805. https://doi.org/10.1002/ejic.202100678.
[1]
J. Bizeau, D. Mertz, Design and applications of protein delivery systems in nanomedicine and tissue engineering, Advances in Colloid and Interface Science. 287 (2021) 102334. https://doi.org/10.1016/j.cis.2020.102334.
[1]
M.O. Besenhard, L. Panariello, C. Kiefer, A.P. LaGrow, L. Storozhuk, F. Perton, S. Bégin, D. Mertz, N.T.K. Thanh, A. Gavriilidis, Small iron oxide nanoparticles as MRI T-1 contrast agent: scalable inexpensive water-based synthesis using a flow reactor dagger, Nanoscale. (2021). https://doi.org/10.1039/d1nr00877c.
[1]
A. Adam, K. Parkhomenko, P. Duenas-Ramirez, C. Nadal, G. Cotin, P.-E. Zorn, P. Choquet, S. Bégin-Colin, D. Mertz, Orienting the Pore Morphology of Core-Shell Magnetic Mesoporous Silica with the Sol-Gel Temperature. Influence on MRI and Magnetic Hyperthermia Properties, Molecules. 26 (2021) 971. https://doi.org/10.3390/molecules26040971.
[1]
Y. Rosales-Cabara, G. Manfredi, G. Schnoering, P.-A. Hervieux, L. Mertz, C. Genet, Optimal protocols and universal time-energy bound in Brownian thermodynamics, Physical Review Research. 2 (2020) 012012. https://doi.org/10.1103/PhysRevResearch.2.012012.
[1]
J.R. Orives, B.P. Pichon, D. Mertz, K. Sartori, S. Bégin-Colin, W.R. Viali, S.J. Lima Ribeiro, M. Nalin, Phosphate glasses containing monodisperse Fe3-delta O4@SiO2 stellate nanoparticles obtained by melt-quenching process, Ceramics International. 46 (2020) 12120–12127. https://doi.org/10.1016/j.ceramint.2020.01.257.
[1]
D. Mertz, S. Harlepp, J. Goetz, D. Begin, G. Schlatter, S. Bégin-Colin, A. Hebraud, Nanocomposite Polymer Scaffolds Responding under External Stimuli for Drug Delivery and Tissue Engineering Applications, Advanced Therapeutics. 3 (2020) 1900143. https://doi.org/10.1002/adtp.201900143.
[1]
B. Li, S. Harlepp, V. Gensbittel, C.J.R. Wells, O. Bringel, J.G. Goetz, S. Bégin-Colin, M. Tasso, D. Begin, D. Mertz, Near infra-red light responsive carbon nanotubes@mesoporous silica for photothermia and drug delivery to cancer cells, Materials Today Chemistry. 17 (2020) 100308. https://doi.org/10.1016/j.mtchem.2020.100308.
[1]
X. Kesse, A. Adam, S. Bégin-Colin, D. Mertz, E. Larquet, T. Gacoin, I. Maurin, C. Vichery, J.-M. Nedelec, Elaboration of Superparamagnetic and Bioactive Multicore–Shell Nanoparticles (γ-Fe2O3@SiO2-CaO): A Promising Material for Bone Cancer Treatment, ACS Applied Materials & Interfaces. 12 (2020) 47820–47830. https://doi.org/10.1021/acsami.0c12769.
[1]
P. Duenas-Ramirez, C. Bertagnolli, R. Muller, K. Sartori, A. Boos, M. Elhabiri, S. Bégin-Colin, D. Mertz, Highly chelating stellate mesoporous silica nanoparticles for specific iron removal from biological media, Journal of Colloid and Interface Science. 579 (2020) 140–151. https://doi.org/10.1016/j.jcis.2020.06.013.
[1]
G. Cotin, F. Perton, C. Petit, S. Sall, C. Kiefer, V. Begin, B. Pichon, C. Lefèvre, D. Mertz, J.-M. Greneche, S. Bégin-Colin, Harnessing Composition of Iron Oxide Nanoparticle: Impact of Solvent-Mediated Ligand-Ligand Interaction and Competition between Oxidation and Growth Kinetics, Chemistry of Materials. 32 (2020) 9245–9259. https://doi.org/10.1021/acs.chemmater.0c03041.
[1]
J. Wallyn, N. Anton, D. Mertz, S. Bégin-Colin, F. Perton, C.A. Serra, F. Franconi, L. Lemaire, M. Chiper, H. Libouban, N. Messaddeq, H. Anton, T.F. Vandamme, Magnetite- and Iodine-Containing Nanoemulsion as a Dual Modal Contrast Agent for X-ray/Magnetic Resonance Imaging, ACS Applied Materials & Interfaces. 11 (2019) 403–416. https://doi.org/10.1021/acsami.8b19517.
[1]
F. Perton, S. Harlepp, G. Follain, K. Parkhomenko, J.G. Goetz, S. Bégin-Colin, D. Mertz, Wrapped stellate silica nanocomposites as biocompatible luminescent nanoplatforms assessed in vivo, Journal of Colloid and Interface Science. 542 (2019) 469–482. https://doi.org/10.1016/j.jcis.2019.01.098.
[1]
F. Perton, M. Tasso, G.A. Munoz Medina, M. Menard, C. Blanco-Andujar, E. Portiansky, M.B. Fernandez van Raap, D. Begin, F. Meyer, S. Bégin-Colin, D. Mertz, Fluorescent and magnetic stellate mesoporous silica for bimodal imaging and magnetic hyperthermia, Applied Materials Today. 16 (2019) 301–314. https://doi.org/10.1016/j.apmt.2019.06.006.
[1]
M. Menard, F. Meyer, C. Affolter-Zbaraszczuk, M. Rabineau, A. Adam, P.D. Ramirez, S. Bégin-Colin, D. Mertz, Design of hybrid protein-coated magnetic core-mesoporous silica shell nanocomposites for MRI and drug release assessed in a 3D tumor cell model, Nanotechnology. 30 (2019) 174001. https://doi.org/10.1088/1361-6528/aafe1c.
[1]
M. Ménard, F. Meyer, K. Parkhomenko, C. Leuvrey, G. Francius, S. Bégin-Colin, D. Mertz, Mesoporous silica templated-albumin nanoparticles with high doxorubicin payload for drug delivery assessed with a 3-D tumor cell model, Biochimica et Biophysica Acta (BBA) - General Subjects. 1863 (2019) 332–341. https://doi.org/10.1016/j.bbagen.2018.10.020.
[1]
Z. Ferjaoui, E.J. Al Dine, A. Kulmukhamedova, L. Bezdetnaya, C.S. Chan, R. Schneider, F. Mutelet, D. Mertz, S. Bégin-Colin, F. Quiles, E. Gaffet, H. Alem, Doxorubicin-Loaded Thermoresponsive Superparamagnetic Nanocarriers for Controlled Drug Delivery and Magnetic Hyperthermia Applications, ACS Applied Materials & Interfaces. 11 (2019) 30610–30620. https://doi.org/10.1021/acsami.9b10444.
[1]
G. Cotin, F. Perton, C. Blanco-Andujar, B. Pichon, D. Mertz, S. Bégin-Colin, Design of Anisotropic Iron-Oxide-Based Nanoparticles for Magnetic Hyperthermia, in: R. Fratila, J. DeLaFuente (Eds.), NANOMATERIALS FOR MAGNETIC AND OPTICAL HYPERTHERMIA APPLICATIONS / Editd by R.M. Fratila & J.M. De La Fuente, 2019: pp. 41–60. 10.1016/B978-0-12-813928-8.00002-8.
[1]
G. Cotin, C. Blanco-Andujar, D.-V. Nguyen, C. Affolter, S. Boutry, A. Boos, P. Ronot, B. Uring-Lambert, P. Choquet, P.E. Zorn, D. Mertz, S. Laurent, R.N. Muller, F. Meyer, D.F. Flesch, S. Bégin-Colin, Dendron based antifouling, MRI and magnetic hyperthermia properties of different shaped iron oxide nanoparticles, Nanotechnology. 30 (2019) 374002. https://doi.org/10.1088/1361-6528/ab2998.
[1]
C. Wells, O. Vollin-Bringel, V. Fiegel, S. Harlepp, B. Van der Schueren, S. Bégin-Colin, D. Bégin, D. Mertz, Engineering of Mesoporous Silica Coated Carbon-Based Materials Optimized for an Ultrahigh Doxorubicin Payload and a Drug Release Activated by pH, T, and NIR-light, Advanced Functional Materials. 28 (2018) 1706996. https://doi.org/10.1002/adfm.201706996.
[1]
D. Mertz, S. Bégin-Colin, Encapsulation and Release of Drugs from Magnetic Silica Nanocomposites, in: N. Thanh (Ed.), CLINICAL APPLICATIONS OF MAGNETIC NANOPARTICLES: DESIGN TO DIAGNOSIS MANUFACTURING TO MEDICINE / Edited by N.T.K. Thanh, 2018: pp. 161–172. 10.1201/9781315168258.
[1]
D.S.B. Gomes, L.G. Paterno, A.B.S. Santos, A. Garay V., D. Mertz, S.M. Freitas, M.A.G. Soler, New insights on the formation of gold nanoparticles and Pluronic nanocomposites: Kinetics and thermodynamics parameters, in: Journal of Molecular Liquids, 2018: pp. 181–189. https://doi.org/10.1016/j.molliq.2018.07.042.
[1]
F. Gelle, R. Chirita, D. Mertz, M.V. Rastei, A. Dinia, S. Colis, Guideline to atomically flat TiO2-terminated SrTiO3(001) surfaces, Surface Science. 677 (2018) 39–45. https://doi.org/10.1016/j.susc.2018.06.001.
[1]
V. Fiegel, S. Harlepp, S. Bégin-Colin, D. Bégin, D. Mertz, Design of Protein-Coated Carbon Nanotubes Loaded with Hydrophobic Drugs through Sacrificial Templating of Mesoporous Silica Shells, Chemistry-a European Journal. 24 (2018) 4662–4670. https://doi.org/10.1002/chem.201705845.
[1]
G. Cotin, C. Kiefer, F. Perton, M. Boero, B. Özdamar, A. Bouzid, G. Ori, C. Massobrio, D. Begin, B. Pichon, D. Mertz, S. Bégin-Colin, Evaluating the Critical Roles of Precursor Nature and Water Content When Tailoring Magnetic Nanoparticles for Specific Applications, ACS Appl. Nano Mater. 1 (2018) 4306–4316. https://doi.org/10.1021/acsanm.8b01123.
[1]
G. Cotin, C. Kiefer, F. Perton, D. Ihiawakrim, C. Blanco-Andujar, S. Moldovan, C. Lefèvre, O. Ersen, B. Pichon, D. Mertz, S. Bégin-Colin, Unravelling the Thermal Decomposition Parameters for The Synthesis of Anisotropic Iron Oxide Nanoparticles, Nanomaterials. 8 (2018) 881. https://doi.org/10.3390/nano8110881.