Bio-Photonics and Ultrafast Molecular Dynamics (BioDyn)

The BioDyn team (Bio-photonics and ultrafast molecular Dynamics) develops experimental tools for femtosecond spectroscopy in the field of physical chemistry, to investigate the photoreactivity of (bio)organic or metal-organic molecules in the condensed phase. Typical processes of interest are photoreactions enabling photo-electric or photo-mechanical energy conversions at the molecular scale. Such photoreactions have applications in material science (e.g. photovoltaic devices, molecular switches, or motors), but they are also at work in biological systems (photosynthesis, vision). Among photoreactions of interest are (i)  photoinduced charge transfer or (ii)  ultrafast photo-isomerization reactions. The investigation of ultrafast photoreactions with fs laser pulses reveals the interplay between (coherent) electronic or vibrational dynamics and environmental effects, and how this interplay controls the photoreactions yield.

Besides, in the 3rd research axis called “biophotonics,” we explore physical chemistry at the interface between nanoscience and living matter. More specifically, we investigate the environment-sensitive photoreactivity of organic compounds that may be exploited to probe local interactions in biomolecules. We also investigate ultrafast excitation energy transfer reactions in functional, synthetic nanoparticles behaving like efficient light-harvesting antennas.

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The team in Nov. 2022 at the GDR UP conference

Research Activities

Position Open

  • Openings: Post-doc in femtosecond XPS of bio-mimetic photoswitches (M/F). Link
  • For Internship, PhD positions, and Postdoc positions, contact Stefan Haacke and Jeremie Leonard

Recent updates

  • Ronan Viel won the 2nd place poster prize (100€) at the ITI QMat scientific day 2023. Congratulations!!!
  •  Ilias Nikolinakos received his Doctoral diploma at the PhD ceremony 2023, University of Strasbourg Congratulations!!!
The summer BBQ Party of the group, June 2023

Team members :

PhD student, Ultrafast Optics and Nanophotonics (DON)hussain.althubyani@ipcms.unistra.fr
Phone: +33(0)3 88 10 71 94Office: 2405
Postdoctoral fellow, Ultrafast Optics and Nanophotonics (DON)xingjie.fu@ipcms.unistra.fr
Phone: +33(0)3 88 10 70 89Office: 1028
Postdoctoral fellow, Ultrafast Optics and Nanophotonics (DON)amira.gharbi@ipcms.unistra.fr
Phone: +33(0)3 88 10 71 63Office: 2052
Professor, Ultrafast Optics and Nanophotonics (DON)Stefan.Haacke@ipcms.unistra.fr
Phone: +33(0)3 88 10 71 71, +33(0)3 88 10 70 54Office: 2029
See personal page
PhD student, Ultrafast Optics and Nanophotonics (DON)krystyna.herasymenko@etu.unistra.fr
Phone: +33(0)3 88 10 71 63Office: 2052
Postdoctoral fellow, Ultrafast Optics and Nanophotonics (DON)mate.kurucz@ipcms.unistra.fr
Phone: /Office: 2109
Senior Researcher, Ultrafast Optics and Nanophotonics (DON)Jeremie.Leonard@ipcms.unistra.fr
Phone: +33(0)3 88 10 72 43, +33(0)3 88 10 70 54Office: 2042
See personal page
PhD student, Ultrafast Optics and Nanophotonics (DON)thomas.meric@ipcms.unistra.fr
Phone: /Office: 2109
PhD student, Ultrafast Optics and Nanophotonics (DON)matthew.mgbukwu@ipcms.unistra.fr
Phone: +33(0)3 88 10 71 63Office: 2052
PhD student, Ultrafast Optics and Nanophotonics (DON)simon.rinconcelis@ipcms.unistra.fr
Phone: /Office: 2109
PhD student, Ultrafast Optics and Nanophotonics (DON)ronan.viel@ipcms.unistra.fr
Phone: +33(0)3 88 10 71 63Office: 2052
Ilias Nikolinakos received his Doctoral diploma at the PhD ceremony 2023,

Recent publications :

[1]
D. Agathangelou, Y. Orozco-Gonzalez, M. del Carmen Marin, P.P. Roy, J. Brazard, H. Kandori, K.-H. Jung, J. Léonard, T. Buckup, N. Ferre, M. Olivucci, S. Haacke, Effect of point mutations on the ultrafast photo-isomerization of Anabaena sensory rhodopsin, in: Faraday Discussions, 2018: pp. 55–75. https://doi.org/10.1039/c7fd00200a.
[1]
D. Agathangelou, Y. El-Khoury, J. Brazard, O. Crégut, S. Haacke, G. Cerullo, J. Léonard, Towards broadband two-Dimensional electronic spectroscopy with similar to 8 fs phase-locked pulses at 400 nm, in: Cerullo, G and Ogilvie, J and Kartner, F and Khalil, M and Li, R (Ed.), XXI INTERNATIONAL CONFERENCE ON ULTRAFAST PHENOMENA 2018 (UP 2018), E D P SCIENCES, 2019. https://doi.org/10.1051/epjconf/201920503006.
[1]
D. Agathangelou, Y. Orozco-Gonzalez, M. del C.M. Perez, J. Brazard, H. Kandori, K.-H. Jung, J. Léonard, Jérémie, N. Ferre, M. Olivucci, S. Haacke, Anabaena Sensory Rhodopsin: Effect of point mutations on PSBR photo-isomerization speed, in: Cerullo, G and Ogilvie, J and Kartner, F and Khalil, M and Li, R (Ed.), XXI INTERNATIONAL CONFERENCE ON ULTRAFAST PHENOMENA 2018 (UP 2018), E D P SCIENCES, 2019. https://doi.org/10.1051/epjconf/201920510004.
[1]
D. Agathangelou, P.P. Roy, M. del C. Marin, N. Ferre, M. Olivucci, T. Buckup, J. Léonard, S. Haacke, Sub-picosecond C=C bond photo-isomerization: evidence for the role of excited state mixing, Comptes Rendus Physique 22 (2021) 111–138. https://doi.org/10.5802/crphys.41.
[1]
M. Ali, B. Boff, J.-T. Issenhuth, A. Boos, N. Potier, S. Harlepp, C. Sirlin, Thermodynamics and Mechanism of Action of a Series of Organoruthenium Anticancer Reagents, International Journal of Advance in Medical Science 1 (2013) 45–48. http://www.seipub.org/ams/paperInfo.aspx?ID=6595.
[1]
H. Anton, S. Harlepp, C. Ramspacher, D. Wu, F. Monduc, S. Bhat, M. Liebling, C. Paoletti, G. Charvin, J.B. Freund, J. Vermot, Pulse propagation by a capacitive mechanism drives embryonic blood flow, Development 140 (2013) 4426–4434. https://doi.org/10.1242/dev.096768.
[1]
F. Aquilante, J. Autschbach, R.K. Carlson, L.F. Chibotaru, M.G. Delcey, L. De Vico, I.F. Galvan, N. Ferre, L.M. Frutos, L. Gagliardi, M. Garavelli, A. Giussani, C.E. Hoyer, G. Li Manni, H. Lischka, D. Ma, P.A. Malmqvist, T. Mueller, A. Nenov, M. Olivucci, T.B. Pedersen, D. Peng, F. Plasser, B. Pritchard, M. Reiher, I. Rivalta, I. Schapiro, J. Segarra-Marti, M. Stenrup, D.G. Truhlar, L. Ungur, A. Valentini, S. Vancoillie, V. Veryazov, V.P. Vysotskiy, O. Weingart, F. Zapata, R. Lindh, Molcas 8: New capabilities for multiconfigurational quantum chemical calculations across the periodic table, Journal of Computational Chemistry 37 (2016) 506–541. https://doi.org/10.1002/jcc.24221.
[1]
A.S. Azevedo, G. Follain, S. Patthabhiraman, S. Harlepp, J.G. Goetz, Metastasis of circulating tumor cells: Favorable soil or suitable biomechanics, or both?, Cell Adhesion & Migration 9 (2015) 345–356. https://doi.org/10.1080/19336918.2015.1059563.
[1]
Y. Bai, J. Qin, L. Shi, J. Zhang, M. Wang, Y. Zhan, H. Zou, S. Haacke, X. Hou, J. Zi, B. Hu, Amplified Spontaneous Emission Realized by Cogrowing Large/Small Grains with Self-Passivating Defects and Aligning Transition Dipoles, Advanced Optical Materials 7 (2019) 1900345. https://doi.org/10.1002/adom.201900345.
[1]
T. Baron, W. Naim, I. Nikolinakos, B. Andrin, Y. Pellegrin, D. Jacquemin, S. Haacke, F. Sauvage, F. Odobel, Transparent and Colorless Dye-Sensitized Solar Cells Based on Pyrrolopyrrole Cyanine Sensitizers, Angewandte Chemie-International Edition 61 (2022) e202207459. https://doi.org/10.1002/anie.202207459.
[1]
T. Baron, W. Naim, M. Kurucz, I. Nikolinakos, B. Andrin, Y. Pellegrin, D. Jacquemin, S. Haacke, F. Sauvage, F. Odobel, Transparent and colorless DSSCs featuring thienyl-pyrrolopyrrole cyanine sensitizers, Journal of Materials Chemistry A 11 (2023) 16767–16775. https://doi.org/10.1039/d3ta02043f.
[1]
V. Bhat, R. Cogdell, C.E. Crespo-Hernández, A. Datta, A. De, S. Haacke, J. Helliwell, R. Improta, J. Joseph, T. Karsili, B. Kohler, R. Krishnan, M. L, F. Lewis, I. Mandal, D. Markovitsi, P.P. Mishra, S. Paul, G. Periyasamy, P.I. Pradeepkumar, P. Roy Chowdhury, M. Sarangi, D. Sasikumar, I. Schapiro, G.F.X. Schertler, I. Schlichting, J. Segarra-Martí, R. Swaminathan, V. V, R. van Grondelle, R. Varghese, R. Venkatramani, Photocrosslinking between nucleic acids and proteins: general discussion, in: Faraday Discussions, 2018: pp. 283–306. https://doi.org/10.1039/C8FD90005A.
[1]
A. Brion, J. Chaud, J. Léonard, F. Bolze, S. Chassaing, B. Frisch, B. Heurtault, A. Kichler, A. Specht, Red Light-Responsive Upconverting Nanoparticles for Quantitative and Controlled Release of a Coumarin-Based Prodrug., Advanced Healthcare Materials Early access (2022) e2201474–e2201474. https://doi.org/10.1002/adhm.202201474.
[1]
A. Brion, J. Chaud, M. Klimezak, F. Bolze, L. Ohlmann, J. Léonard, S. Chassaing, B. Frisch, A. Kichler, B. Heurtault, A. Specht, Photoactivatable Liposomes for Blue to Deep Red Light-Activated Surface Drug Release: Application to Controlled Delivery of the Antitumoral Drug Melphalan., Bioconjugate Chemistry 34 (2023) 1304–1315. https://doi.org/10.1021/acs.bioconjchem.3c00197.
[1]
T. Buckup, J. Léonard, Multidimensional Vibrational Coherence Spectroscopy, Topics in Current Chemistry 376 (2018) 35. https://doi.org/10.1007/s41061-018-0213-4.
[1]
A. Cannizzo, J. Léonard, S. Haacke, Ultrafast Functional Dynamics in Proteins: Local Molecular Reporters and Femtosecond 2D Spectroscopy, in: I. Burghardt, S. Haacke (Eds.), ULTRAFAST DYNAMICS AT THE NANOSCALE: BIOMOLECULES AND SUPRAMOLECULAR ASSEMBLIES, 2017: pp. 207–253.
[1]
C. Cebrían, M. Pastore, A. Monari, X. Assfeld, P.C. Gros, S. Haacke, Ultrafast Spectroscopy of Fe(II) Complexes Designed for Solar Energy Conversion: Current Status and Open Questions, ChemPhysChem 23 (2022) e202100659. https://doi.org/https://doi.org/10.1002/cphc.202100659.
[1]
A. Chandra, R. Cogdell, C.E. Crespo-Hernández, A. Datta, A. Giussani, S. Haacke, J. Helliwell, R. Improta, R.S. Jayasree, M. Jones, T. Karsili, B. Kohler, M. L, I. Mandal, D. Markovitsi, H. Medhi, P.P. Mishra, P.I. Pradeepkumar, P. Roy Chowdhury, M. Sarangi, I. Schapiro, I. Schlichting, J. Segarra-Martí, A. Sharma, V. V, R. van Grondelle, A. Watts, Light induced damage and repair in nucleic acids and proteins: general discussion, in: Faraday Discussions, 2018: pp. 389–408. https://doi.org/10.1039/C8FD90006J.
[1]
A. Chandra, A. Chattopadhyay, R. Cogdell, A. Datta, A. De, S. Dhamija, M. Golla, S. Haacke, M. Hariharan, J. Helliwell, R. Improta, R.S. Jayasree, M. Jones, J. Joseph, T. Karsili, B. Kohler, R. Krishnan, I. Mandal, D. Markovitsi, H. Medhi, P.P. Mishra, P. Roy Chowdhury, M. Sarangi, I. Schlichting, J. Seddon, A. Sharma, A. Siriki, R. Swaminathan, R. van Grondelle, R. Varghese, R. Venkatramani, A. Watts, Bionanophotonics: general discussion, in: Faraday Discussions, 2018: pp. 491–512. https://doi.org/10.1039/C8FD90007H.
[1]
L. Charbonniere, S. Haacke, 28th International Conference on Photochemistry (ICP 2017): an introduction by the Guest Editors, Photochemical & Photobiological Sciences 17 (2018) 1280–1281. https://doi.org/10.1039/c8pp90040j.
[1]
A. Chattopadhyay, R. Cogdell, C.E. Crespo-Hernández, A. Datta, A. De, S. Haacke, M. Hariharan, J. Helliwell, A. Hughes, R. Improta, M. Jones, J. Joseph, T. Karsili, B. Kohler, R. Krishnan, A. Kuriakose, M. L, D. Markovitsi, H. Medhi, G. Periyasamy, P.I. Pradeepkumar, P. Roy Chowdhury, M. Sarangi, I. Schapiro, G.F.X. Schertler, I. Schlichting, J. Segarra-Martí, R. Swaminathan, V. V, R. van Grondelle, R.K. Venkatraman, R. Venkatramani, A. Watts, Light induced charge and energy transport in nucleic acids and proteins: general discussion, in: Faraday Discussions, 2018: pp. 153–180. https://doi.org/10.1039/C8FD90004C.
[1]
A. Cheminal, J. Léonard, S.Y. Kim, K.H. Jung, H. Kandori, S. Haacke, Steady state emission of the fluorescent intermediate of Anabaena Sensory Rhodopsin as a function of light adaptation conditions, Chemical Physics Letters 587 (2013) 75–80. https://doi.org/10.1016/j.cplett.2013.09.044.
[1]
A. Cheminal, S.Y. Kim, J. Léonard, H. Kandori, K.H. Jung, S. Haacke, Anabaena sensory Rhodopsin: Excited state dynamics of a natural photoswitch studied by steady state fluorescence and ultrafast spectroscopy, in: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Dallas, TX, USA, 2014.
[1]
A. Cheminal, J. Léonard, S.-Y. Kim, K.-H. Jung, H. Kandori, S. Haacke, 100 fs photo-isomerization with vibrational coherences but low quantum yield in Anabaena Sensory Rhodopsin, Physical Chemistry Chemical Physics 17 (2015) 25429–25439. https://doi.org/10.1039/C5CP04353K.
[1]
J. Conyard, K. Voltz, T. Gelot, P. Touron-Touceda, O. Crégut, J. Léonard, R. Stote, S. Haacke, Local structural dynamics of DNA hairpins studied by ultrafast fluorescence spectroscopy and molecular dynamics simulations, in: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014.
[1]
M. Darari, E. Domenichini, A. Frances-Monerris, C. Cebrian, K. Magra, M. Beley, M. Pastore, A. Monari, X. Assfeld, S. Haacke, P.C. Gros, Iron(ii) complexes with diazinyl-NHC ligands: impact of pi-deficiency of the azine core on photophysical properties, Dalton Transactions 48 (2019) 10915–10926. https://doi.org/10.1039/c9dt01731c.
[1]
M. Darari, A. Frances-Monerris, B. Marekha, A. Doudouh, E. Wenger, A. Monari, S. Haacke, P.C. Gros, Towards Iron(II) Complexes with Octahedral Geometry: Synthesis, Structure and Photophysical Properties, Molecules 25 (2020) 5991. https://doi.org/10.3390/molecules25245991.
[1]
P. Didier, J. Kuchlyan, L. Martinez-Fernandez, P. Gosset, J. Léonard, Y. Tor, R. Improta, Y. Mely, Deciphering the pH-dependence of ground- and excited-state equilibria of thienoguanine, Physical Chemistry Chemical Physics 22 (2020) 7381–7391. https://doi.org/10.1039/c9cp06931c.
[1]
R.B. Doak, R.L. Shoeman, A. Gorel, T.R.M. Barends, B. Marekha, S. Haacke, S. Nizinski, I. Schlichting, Dynamic catcher for stabilization of high-viscosity extrusion jets, Journal of Applied Crystallography 56 (2023) 903–907. https://doi.org/10.1107/S1600576723003795.
[1]
E. Domenichini, S. Doria, M. Di Donato, L. Cupellini, G. Biagiotti, A. Iagatti, L. Bussotti, B. Mennucci, S. Cicchi, P. Foggi, Steric hindrances and spectral distributions affecting energy transfer rate: A comparative study on specifically designed donor-acceptor pairs, Dyes and Pigments 174 (2020). https://doi.org/10.1016/j.dyepig.2019.108010.
[1]
L. Donato, A. Mourot, C.M. Davenport, C. Herbivo, D. Warther, J. Léonard, F. Bolze, J.-F. Nicoud, R.H. Kramer, M. Goeldner, A. Specht, Water-Soluble, Donor-Acceptor Biphenyl Derivatives in the 2-(o-Nitrophenyl)propyl Series: Highly Efficient Two-Photon Uncaging of the Neurotransmitter gamma-Aminobutyric Acid at lambda=800 nm, Angewandte Chemie-International Edition 51 (2012) 1840–1843. https://doi.org/10.1002/anie.201106559.
[1]
T. Duchanois, T. Etienne, C. Cebrian, L. Liu, A. Monari, M. Beley, X. Assfeld, S. Haacke, P.C. Gros, An Iron-Based Photosensitizer with Extended Excited-State Lifetime: Photophysical and Photovoltaic Properties, European Journal of Inorganic Chemistry (2015) 2469–2477. https://doi.org/10.1002/ejic.201500142.
[1]
T. Duchanois, L. Liu, M. Pastore, A. Monari, C. Cebrián, Y. Trolez, M. Darari, K. Magra, A. Francés-Monerris, E. Domenichini, M. Beley, X. Assfeld, S. Haacke, P.C. Gros, NHC-Based Iron Sensitizers for DSSCs, Inorganics 6 (2018) 63. https://doi.org/10.3390/inorganics6020063.
[1]
G. Fanciullo, I. Conti, P. Didier, A. Klymchenko, J. Léonard, M. Garavelli, I. Rivalta, Modelling quenching mechanisms of disordered molecular systems in the presence of molecular aggregates, Physical Chemistry Chemical Physics 24 (2022) 1787–1794. https://doi.org/10.1039/d1cp04260b.
[1]
V. Fiegel, S. Harlepp, S. Bégin-Colin, D. Bégin, D. Mertz, Design of Protein-Coated Carbon Nanotubes Loaded with Hydrophobic Drugs through Sacrificial Templating of Mesoporous Silica Shells, Chemistry-a European Journal 24 (2018) 4662–4670. https://doi.org/10.1002/chem.201705845.
[1]
M. Filatov Gulak, M. Paolino, R. Pierron, A. Cappelli, G. Giorgi, J. Léonard, M. Huix-Rotllant, N. Ferre, X. Yang, D. Kaliakin, A. Blanco-Gonzalez, M. Olivucci, Towards the engineering of a photon-only two-stroke rotary molecular motor., Nature Communications 13 (2022) 6433. https://doi.org/10.1038/s41467-022-33695-x.
[1]
M. Filatov Gulak, M. Paolino, R. Pierron, A. Cappelli, G. Giorgi, J. Léonard, M. Huix-Rotllant, N. Ferre, X. Yang, D. Kaliakin, A. Blanco-Gonzalez, M. Olivucci, Author Correction: Towards the engineering of a photon-only two-stroke rotary molecular motor., Nature Communications 13 (2022) 7541–7541. https://doi.org/10.1038/s41467-022-35006-w.
[1]
G. Follain, L. Mercier, N. Osmani, S. Harlepp, J.G. Goetz, Seeing is believing - multi-scale spatio-temporal imaging towards in vivo cell biology, Journal of Cell Science 130 (2017) 23–38. https://doi.org/10.1242/jcs.189001.
[1]
G. Follain, N. Osmani, A.S. Azevedo, G. Allio, L. Mercier, M.A. Karreman, G. Solecki, M.J.G. Leon, O. Lefebvre, N. Fekonja, C. Hille, V. Chabannes, G. Dolle, T. Metivet, F.D. Hovsepian, C. Prudhomme, A. Pichot, N. Paul, R. Carapito, S. Bahram, B. Ruthensteiner, A. Kemmling, S. Siemonsen, T. Schneider, J. Fiehler, M. Glatzel, F. Winkler, Y. Schwab, K. Pantel, S. Harlepp, J.G. Goetz, Hemodynamic Forces Tune the Arrest, Adhesion, and Extravasation of Circulating Tumor Cells, Developmental Cell 45 (2018) 33+. https://doi.org/10.1016/j.devcel.2018.02.015.
[1]
G. Follain, N. Osmani, C. Fuchs, G. Allio, S. Harlepp, J. Goetz, Using the Zebrafish Embryo to Dissect the Early Steps of the Metastasis Cascade, in: Methods in Molecular Biology (Clifton, N.J.), 2018: pp. 195–211. http://dx.doi.org/10.1007/978-1-4939-7701-7_15.
[1]
A. Frances-Monerris, K. Magra, M. Darari, C. Cebrian, M. Beley, E. Domenichini, S. Haacke, M. Pastore, X. Assfeld, P.C. Gros, A. Monari, Synthesis and Computational Study of a Pyridylcarbene Fe(II) Complex: Unexpected Effects of fac/mer Isomerism in Metal-to-Ligand Triplet Potential Energy Surfaces, Inorganic Chemistry 57 (2018) 10431–10441. https://doi.org/10.1021/acs.inorgchem.8b01695.
[1]
I.F. Galvan, M. Vacher, A. Alavi, C. Angeli, F. Aquilante, J. Autschbach, J.J. Bao, S.I. Bokarev, N.A. Bogdanov, R.K. Carlson, L.F. Chibotaru, J. Creutzberg, N. Dattani, M.G. Delcey, S.S. Dong, A. Dreuw, L. Freitag, L. Manuel Frutos, L. Gagliardi, F. Gendron, A. Giussani, L. Gonzalez, G. Grell, M. Guo, C.E. Hoyer, M. Johansson, S. Keller, S. Knecht, G. Kovacevic, E. Kallman, G. Li Manni, M. Lundberg, Y. Ma, S. Mai, J.P. Malhado, P.A. Malmqvist, P. Marquetand, S.A. Mewes, J. Norell, M. Olivucci, M. Oppel, Q.M. Phung, K. Pierloot, F. Plasser, M. Reiher, A.M. Sand, I. Schapiro, P. Sharma, C.J. Stein, L.K. Sorensen, D.G. Truhlar, M. Ugandi, L. Ungur, A. Valentini, S. Vancoillie, V. Veryazov, O. Weser, T.A. Wesolowski, P.-O. Widmark, S. Wouters, A. Zech, J.P. Zobel, R. Lindh, OpenMolcas: From Source Code to Insight, Journal of Chemical Theory and Computation 15 (2019) 5925–5964. https://doi.org/10.1021/acs.jctc.9b00532.
[1]
C. García-Iriepa, P. Gosset, R. Berraud-Pache, M. Zemmouche, G. Taupier, K.D. Dorkenoo, P. Didier, J. Léonard, N. Ferré, I. Navizet, Simulation and Analysis of the Spectroscopic Properties of Oxyluciferin and Its Analogues in Water, Journal of Chemical Theory and Computation 14 (2018) 2117–2126. https://doi.org/10.1021/acs.jctc.7b01240.
[1]
C. Garcia-Iriepa, M. Gueye, J. Léonard, D. Martinez-Lopez, P.J. Campos, L.M. Frutos, D. Sampedro, M. Marazzi, A biomimetic molecular switch at work: coupling photoisomerization dynamics to peptide structural rearrangement, Physical Chemistry Chemical Physics 18 (2016) 6742–6753. https://doi.org/10.1039/C5CP07599H.
[1]
C. Garcia-Iriepa, D. Sampedro, F. Mendicuti, J. Léonard, L. Manuel Frutos, Photoreactivity Control Mediated by Molecular Force Probes in Stilbene, Journal of Physical Chemistry Letters 10 (2019) 1063–1067. https://doi.org/10.1021/acs.jpclett.8b03802.
[1]
T. Gelot, P. Touron-Touceda, O. Crégut, J. Léonard, S. Haacke, Ultrafast Site-Specific Fluorescence Quenching of 2-Aminopurine in a DNA Hairpin Studied by Femtosecond Down-Conversion, Journal of Physical Chemistry A 116 (2012) 2819–2825. https://doi.org/10.1021/jp212187m.
[1]
P. Gosset, G. Taupier, O. Crégut, J. Brazard, Y. Mely, K.-D. Dorkenoo, J. Léonard, P. Didier, Excited-State Proton Transfer in Oxyluciferin and Its Analogues, Journal of Physical Chemistry Letters 11 (2020) 3653–3659. https://doi.org/10.1021/acs.jpclett.0c00839.
[1]
M.L. Gruenbein, M. Stricker, G. Nass Kovacs, M. Kloos, R.B. Doak, R.L. Shoeman, J. Reinstein, S. Lecler, S. Haacke, I. Schlichting, Illumination guidelines for ultrafast pump-probe experiments by serial femtosecond crystallography, Nature Methods 17 (2020) 681–684. https://doi.org/10.1038/s41592-020-0847-3.
[1]
N. Grytsyk, D. Cianfarani, O. Crégut, L. Richert, C. Boudier, N. Humbert, P. Didier, Y. Mely, J. Léonard, Kinetics of protein-assisted nucleic acid interconversion monitored by transient time resolved fluorescence in microfluidic droplets, Nucleic Acids Research 49 (2021) e111. https://doi.org/10.1093/nar/gkab687.
[1]
M. Gueye, J. Nillon, O. Crégut, J. Léonard, Broadband UV-Vis vibrational coherence spectrometer based on a hollow fiber compressor, Review of Scientific Instruments 87 (2016) 093109. https://doi.org/http://dx.doi.org/10.1063/1.4962699.

Experimental Set-Ups and Developments

Bio-photonics

ENERGY CONVERSION

Ultrafast photoisomerization