Biophysique et dynamique de nanostructures organiques (BIODYN)

The Biodyn team (Biophysics and ultrafast Dynamics) develops experimental tools for time-resolved spctroscopy and micromanipulation/microscopy in the fields of physical chemistry and biophysics.

We use ultrafast spectroscopy to investigate the photoreactivity of (bio)organic compounds and nanostructures. Typical processes of interest are photo-electric or photo-mechanical energy conversions at the molecular scale, which have applications in material science (e.g. photovoltaic devices, nanomachines), and are also exploited in biological systems (photosynthesis, vision). From the physical point of view, these processes rely on ultrafast, photoinduced energy and charge transfer or ultrafast photoinduced isomerization reactions in organic molecules interacting with their environment (solution, functional organic film, protein, etc…). We implement non-linear, femtosecond UV-Vis spectroscopy to investigate the mechanisms of such ultrafast processes.

Besides, the environment-sensitive photoreactivity of organic compounds may be exploited to probe local interactions in biomolecules. Hence one of our contributions to biophysics resides in exploiting time-resolved spectroscopy to unravel biomolecular structures or interactions.

Overmore, our biophysical research activity also focuses on the cellular or organism scales. To this end, we also develop microscopy and micromanipulation schemes (e.g. optical tweezers) to probe cell adhesion in the context of development biology or tumor progression.

Membres de l’équipe :

Doctorante, Optique Ultra-rapide et Nanophotonique (DON)amira.gharbi@ipcms.unistra.fr
Tél: +33(0)3 88 10 71 63Bureau: 2052
Professeur, Optique Ultra-rapide et Nanophotonique (DON)Stefan.Haacke@ipcms.unistra.fr
Tél: +33(0)3 88 10 71 71, +33(0)3 88 10 70 54Bureau: 2029
Voir la page personnelle
Doctorante, Optique Ultra-rapide et Nanophotonique (DON)krystyna.herasymenko@etu.unistra.fr
Tél: +33(0)3 88 10 71 63Bureau: 2052
Post-doctorant, Optique Ultra-rapide et Nanophotonique (DON)mate.kurucz@ipcms.unistra.fr
Tél: +33(0)3 88 10 71 63Bureau: 2052
Directeur de Recherche, Optique Ultra-rapide et Nanophotonique (DON)Jeremie.Leonard@ipcms.unistra.fr
Tél: +33(0)3 88 10 72 43, +33(0)3 88 10 70 54Bureau: 2042
Voir la page personnelle
Doctorant, Optique Ultra-rapide et Nanophotonique (DON)matthew.mgbukwu@ipcms.unistra.fr
Tél: +33(0)3 88 10 71 63Bureau: 2052
Doctorant, Optique Ultra-rapide et Nanophotonique (DON)ronan.viel@ipcms.unistra.fr
Tél: +33(0)3 88 10 71 94Bureau: 2405
The team in Oct. 2016

Publications récentes :

[1]
T. Baron, W. Naim, I. Nikolinakos, B. Andrin, Y. Pellegrin, D. Jacquemin, S. Haacke, F. Sauvage, F. Odobel, Transparent and Colorless Dye-Sensitized Solar Cells Based on Pyrrolopyrrole Cyanine Sensitizers, Angewandte Chemie-International Edition. 61 (2022) e202207459. https://doi.org/10.1002/anie.202207459.
[1]
A. Brion, J. Chaud, J. Léonard, F. Bolze, S. Chassaing, B. Frisch, B. Heurtault, A. Kichler, A. Specht, Red Light-Responsive Upconverting Nanoparticles for Quantitative and Controlled Release of a Coumarin-Based Prodrug., Advanced Healthcare Materials. Early access (2022) e2201474–e2201474. https://doi.org/10.1002/adhm.202201474.
[1]
C. Cebrían, M. Pastore, A. Monari, X. Assfeld, P.C. Gros, S. Haacke, Ultrafast Spectroscopy of Fe(II) Complexes Designed for Solar Energy Conversion: Current Status and Open Questions, ChemPhysChem. 23 (2022) e202100659. https://doi.org/https://doi.org/10.1002/cphc.202100659.
[1]
G. Fanciullo, I. Conti, P. Didier, A. Klymchenko, J. Léonard, M. Garavelli, I. Rivalta, Modelling quenching mechanisms of disordered molecular systems in the presence of molecular aggregates, Physical Chemistry Chemical Physics. 24 (2022) 1787–1794. https://doi.org/10.1039/d1cp04260b.
[1]
M. Filatov Gulak, M. Paolino, R. Pierron, A. Cappelli, G. Giorgi, J. Léonard, M. Huix-Rotllant, N. Ferre, X. Yang, D. Kaliakin, A. Blanco-Gonzalez, M. Olivucci, Towards the engineering of a photon-only two-stroke rotary molecular motor., Nature Communications. 13 (2022) 6433. https://doi.org/10.1038/s41467-022-33695-x.
[1]
K. Magra, A. Frances-Monerris, C. Cebrian, A. Monari, S. Haacke, P.C. Gros, Bidentate Pyridyl-NHC Ligands: Synthesis, Ground and Excited State Properties of Their Iron(II) Complexes and the Role of the fac/mer Isomerism, European Journal of Inorganic Chemistry. 2022 (2022) e202100818. https://doi.org/10.1002/ejic.202100818.
[1]
A.R. Marri, B. Marekha, T. Penfold, S. Haacke, P.C. Gros, Towards panchromatic Fe(ii) NHC sensitizers via HOMO inversion, Inorganic Chemistry Frontiers. Early access (2022). https://doi.org/10.1039/D2QI01903E.
[1]
M. Paolino, M. Saletti, A. Reale, M. Licciardi, P. Varvara, A. Marquette, J. Léonard, C. Bonechi, A. Donati, G. Giorgi, G. Giuliani, B. Carlotti, F. Ortica, L. Latterini, M. Gentile, E. Paccagnini, M. Olivucci, A. Cappelli, Design, Synthesis and Characterization of a New Visible Light-Sensitive Molecular Switch and its PEGylation Towards a Self-Assembling Molecule., Chemistry-a European Journal. 28 (2022) e202201477. https://doi.org/10.1002/chem.202201477.
[1]
X. Yang, M. Manathunga, S. Gozem, J. Léonard, T. Andruniów, M. Olivucci, Quantum–classical simulations of rhodopsin reveal excited-state population splitting and its effects on quantum efficiency, Nature Chemistry. 14 (2022) 441–449. https://doi.org/10.1038/s41557-022-00892-6.

Femtosecond Instrumentation

New Tools for Biophotonics

Ultrafast photo-isomerization

Photophysics of organic nanostructures for energy conversion applications

Biomolecular Structural Heterogeneity and Dynamics studied by ultrafast spectroscopy